There are now a multitude of sciences where nature is broken up by fairly arbitrary boundaries such as size and location of phenomena. This is due to anthropomorphism. We are human and erroneously think inside our isolated brains that man is the measure of all things, when actually humans and human thinking is a barely 10,000 to 100,000 year event while the universe is clearly somewhere around 14, 000,000,000 years old. Compare those two numbers. More than a million to one.
Some in the past have called for a unification of science. Some have called for cross-disciplinary awareness. The ISGE is an exercise or attempt at both, unification, synthesis, integration.
Here are some slides from a recent conference talk that explain the Basic Idea and the revolutions that it would deliver: